4 papers
Meta-analysis and Topological Perturbation in Interactomic Network for Anti-opioid Addiction Drug Repurposing
Chunhuan Zhang, Sean Cottrell, Benjamin Jones +5
The ongoing opioid crisis highlights the urgent need for novel therapeutic strategies that can be rapidly deployed. This study presents a novel approach to identify potential repur…
Machine learning predictions from unpredictable chaos
Jian Jiang, Long Chen, Lu ke +7
Chaos is omnipresent in nature, and its understanding provides enormous social and economic benefits. However, the unpredictability of chaotic systems is a textbook concept due to…
Proteomic Learning of Gamma-Aminobutyric Acid (GABA) Receptor-Mediated Anesthesia
Jian Jiang, Long Chen, Yueying Zhu +5
Anesthetics are crucial in surgical procedures and therapeutic interventions, but they come with side effects and varying levels of effectiveness, calling for novel anesthetic agen…
Reconstructing the evolution history of networked complex systems
Junya Wang, Yi-Jiao Zhang, Cong Xu +6
The evolution processes of complex systems carry key information in the systems' functional properties. Applying machine learning algorithms, we demonstrate that the historical for…