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stat.ME2025
The permuted score test for robust differential expression analysis
Timothy Barry, Ziang Niu, Eugene Katsevich +1
Negative binomial (NB) regression is a popular method for identifying differentially expressed genes in genomics data, such as bulk and single-cell RNA sequencing data. However, NB…
stat.ME2024
Saddlepoint approximations for plug-in resampling
Ziang Niu, Zhihan Huang, Jyotishka Ray Choudhury +1
Resampling-based procedures can improve on normal approximations in sparse, large-scale testing problems, but their computational cost can be prohibitive. We recognize that several…