13 papers
SAGEAgent: A Self-Evolving Agent for Cost-Aware Modality Acquisition in Multimodal Survival Prediction
Chongyu Qu, Can Cui, Zhengyi Lu +8
Does every cancer patient truly need a complete diagnostic workup for accurate survival prediction? In multimodal clinical oncology, diagnostic modalities follow a clinically manda…
MORI-Seg: Learning Morphological Geometry for Instance Segmentation without Instance Annotations
Leiyue Zhao, Tianyu Shi, Daniel Reisenbuchler +12
Instance-level quantification of kidney functional units is essential for morphometric analysis, yet most publicly available pathology datasets provide only semantic segmentation a…
DUET: Dual-Paradigm Adaptive Expert Triage with Single-cell Inductive Prior for Spatial Transcriptomics Prediction
Junchao Zhu, Ruining Deng, Junlin Guo +11
Inferring spatially resolved gene expression from histology images offers a cost-effective complement to spatial transcriptomics (ST). However, existing methods reduce this task to…
Explainable Pathomics Feature Visualization via Correlation-aware Conditional Feature Editing
Yuechen Yang, Junlin Guo, Ruining Deng +9
Pathomics is a recent approach that offers rich quantitative features beyond what black-box deep learning can provide, supporting more reproducible and explainable biomarkers in di…
MASC: Metal-Aware Sampling and Correction via Reinforcement Learning for Accelerated MRI
Zhengyi Lu, Ming Lu, Chongyu Qu +11
Metal implants in MRI cause severe artifacts that degrade image quality and hinder clinical diagnosis. Traditional approaches address metal artifact reduction (MAR) and accelerated…
AdaFuse: Adaptive Multimodal Fusion for Lung Cancer Risk Prediction via Reinforcement Learning
Chongyu Qu, Zhengyi Lu, Yuxiang Lai +10
Multimodal fusion has emerged as a promising paradigm for disease diagnosis and prognosis, integrating complementary information from heterogeneous data sources such as medical ima…
SCR2-ST: Combine Single Cell with Spatial Transcriptomics for Efficient Active Sampling via Reinforcement Learning
Junchao Zhu, Ruining Deng, Junlin Guo +13
Spatial transcriptomics (ST) is an emerging technology that enables researchers to investigate the molecular relationships underlying tissue morphology. However, acquiring ST data…
HistoWAS: A Pathomics Framework for Large-Scale Feature-Wide Association Studies of Tissue Topology and Patient Outcomes
Yuechen Yang, Junlin Guo, Yanfan Zhu +10
High-throughput "pathomic" analysis of Whole Slide Images (WSIs) offers new opportunities to study tissue characteristics and for biomarker discovery. However, the clinical relevan…
Evaluating New AI Cell Foundation Models on Challenging Kidney Pathology Cases Unaddressed by Previous Foundation Models
Runchen Wang, Junlin Guo, Siqi Lu +12
Accurate cell nuclei segmentation is critical for downstream tasks in kidney pathology and remains a major challenge due to the morphological diversity and imaging variability of r…
DyMorph-B2I: Dynamic and Morphology-Guided Binary-to-Instance Segmentation for Renal Pathology
Leiyue Zhao, Yuechen Yang, Yanfan Zhu +7
Accurate morphological quantification of renal pathology functional units relies on instance-level segmentation, yet most existing datasets and automated methods provide only binar…
ZeroReg3D: A Zero-shot Registration Pipeline for 3D Consecutive Histopathology Image Reconstruction
Juming Xiong, Ruining Deng, Jialin Yue +10
Histological analysis plays a crucial role in understanding tissue structure and pathology. While recent advancements in registration methods have improved 2D histological analysis…
DeepAndes: A Self-Supervised Vision Foundation Model for Multi-Spectral Remote Sensing Imagery of the Andes
Junlin Guo, James R. Zimmer-Dauphinee, Jordan M. Nieusma +16
By mapping sites at large scales using remotely sensed data, archaeologists can generate unique insights into long-term demographic trends, inter-regional social networks, and past…
PySpatial: A High-Speed Whole Slide Image Pathomics Toolkit
Yuechen Yang, Yu Wang, Tianyuan Yao +5
Whole Slide Image (WSI) analysis plays a crucial role in modern digital pathology, enabling large-scale feature extraction from tissue samples. However, traditional feature extract…