83 citations · 87 across the 10 of their papers we have counts for
11 papers
Sharpness-Aware Minimization (SAM) Improves Classification Accuracy of Bacterial Raman Spectral Data Enabling Portable Diagnostics
Kaitlin Zareno, Jarett Dewbury, Siamak K. Sorooshyari +2
Antimicrobial resistance is expected to claim 10 million lives per year by 2050, and resource-limited regions are most affected. Raman spectroscopy is a novel pathogen diagnostic a…
Pic2Spec: Generative Modeling Reconstructs Single Cell Raman Fingerprints from Brightfield Images
Srilakshmi Premachandran, Amit Kumar Bhuyan, Loza F. Tadesse
Single-cell molecular characterization remains a bottleneck in scalable biological analysis because of labeling requirements, limited multiplexing, and reagents that perturb physio…
Deep Speckle Holography Redefines Label-free Nanoparticle Phenotyping
Yanmin Zhu, Yuxing Li, Jingyan Chen +9
Nanoparticle metrology has long been constrained by the assumption that, in mixed and unprocessed fluids, particle size, morphology, composition, and species-specific abundance can…
Non-perturbative Bacterial Identification Directly from Solid Agar Plates Using Raman
Jeong Hee Kim, Jia Dong, Marissa Morales +1
Raman spectroscopy is a promising tool for microbial identification, yet its implementation in microbiology and clinical workflow is still restricted due to the accompanying additi…
Towards Breath Based Diagnostics via Water-mediated Capture of Synthetic Breath Biomarkers in SERS-active Plasmonic Nanogaps
Aditya Garg, Marissa Morales, Aashini Shah +7
Volatile organic compounds (VOCs) are valuable health indicators, with synthetic breath biomarkers offering rapid and disease specific diagnostics. However, their <100 ppb level ex…
Nano-engineered surface enhanced Raman spectroscopy substrates for probing tissue-material interactions
Connie M. Wang, Roberta M. Sabino, Aditya Garg +3
Innovation in biomaterials has brought both breakthroughs and new challenges in medicine, as implant materials have become increasingly multifunctional and complex. One of the grea…
Interplay of Electrostatic Interaction and Steric Repulsion between Bacteria and Gold Surface Influences Raman Enhancement
Jia Dong, Jeong Hee Kim, Isaac Pincus +4
Plasmonic nanostructures have wide applications in photonics including pathogen detection and diagnosis via Surface-Enhanced Raman Spectroscopy (SERS). Despite major role plasmonic…
Universal Spectral Transfer with Physical Prior-Informed Deep Generative Learning
Yanmin Zhu, Loza F. Tadesse
Spectroscopy is a powerful analytical technique for characterizing matter across physical and biological realms1-5. However, its fundamental principle necessitates specialized inst…
Rapid, antibiotic incubation-free determination of tuberculosis drug resistance using machine learning and Raman spectroscopy
Babatunde Ogunlade, Loza F. Tadesse, Hongquan Li +6
Tuberculosis (TB) is the world's deadliest infectious disease, with over 1.5 million deaths annually and 10 million new cases reported each year. The causative organism, Mycobacter…
More than magnetic isolation: Dynabeads as strong Raman reporters towards simultaneous capture and identification of targets
Jongwan Lee, Marissa McDonald, Nikiwe Mhlanga +3
Dynabeads are superparamagnetic particles used for immunomagnetic purification of cells and biomolecules. Post-capture, however, target identification relies on tedious culturing,…
Combining acoustic bioprinting with AI-assisted Raman spectroscopy for high-throughput identification of bacteria in blood
Fareeha Safir, Nhat Vu, Loza F. Tadesse +7
Identifying pathogens in complex samples such as blood, urine, and wastewater is critical to detect infection and inform optimal treatment. Surface-enhanced Raman spectroscopy (SER…