117 citations · 119 across the 2 of their papers we have counts for
2 papers
q-bio.GN2009★ 2 cited
Fundamentally different strategies for transcriptional regulation are revealed by information-theoretical analysis of binding motifs
Leonid A. Mirny, Zeba Wunderlich
To regulate a particular gene, a transcription factor (TF) needs to bind a specific genome location. How is this genome address specified amid the presence of ~10^6-10^9 decoy site…
q-bio.BM2007★ 117 cited
Spatial effects on the speed and reliability of protein-DNA search
Zeba Wunderlich, Leonid A. Mirny
Strong experimental and theoretical evidence shows that transcription factors and other specific DNA-binding proteins find their sites using a two-mode search: alternating between…