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math.ST2024
Constructing optimal treatment length strategies to maximize quality-adjusted lifetimes
Hao Sun, Ashkan Ertefaie, Luke Duttweiler +1
Real-world clinical decision making is a complex process that involves balancing the risks and benefits of treatments. Quality-adjusted lifetime is a composite outcome that combine…
stat.ME2024★ 1 cited
Statistical Operating Characteristics of Current Early Phase Dose Finding Designs with Toxicity and Efficacy in Oncology
Hao Sun, Hsin-Yu Lin, Jieqi Tu +2
Traditional phase I dose finding cancer clinical trial designs aim to determine the maximum tolerated dose (MTD) of the investigational cytotoxic agent based on a single toxicity o…