3 papers
cs.LG2025
BiBLDR: Bidirectional Behavior Learning for Drug Repositioning
Renye Zhang, Mengyun Yang, Qichang Zhao +1
Drug repositioning aims to identify potential new indications for existing drugs to reduce the time and financial costs associated with developing new drugs. Most existing deep lea…
q-bio.GN2025
TopoLa: A Universal Framework to Enhance Cell Representations for Single-cell and Spatial Omics through Topology-encoded Latent Hyperbolic Geometry
Kai Zheng, Shaokai Wang, Yunpei Xu +8
Recent advances in cellular research demonstrate that scRNA-seq characterizes cellular heterogeneity, while spatial transcriptomics reveals the spatial distribution of gene express…
cs.SI2024
TopoLa: a novel embedding framework for understanding complex networks
Kai Zheng, Qilong Feng, Yaohang Li +3
Complex networks, which are the abstractions of many real-world systems, present a persistent challenge across disciplines for people to decipher their underlying information. Rece…