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Interpretable Droplet Digital PCR Assay for Trustworthy Molecular Diagnostics
Yuanyuan Wei, Yucheng Wu, Fuyang Qu +5
Accurate molecular quantification is essential for advancing research and diagnostics in fields such as infectious diseases, cancer biology, and genetic disorders. Droplet digital…
SAM-dPCR: Real-Time and High-throughput Absolute Quantification of Biological Samples Using Zero-Shot Segment Anything Model
Yuanyuan Wei, Shanhang Luo, Changran Xu +8
Digital PCR (dPCR) has revolutionized nucleic acid diagnostics by enabling absolute quantification of rare mutations and target sequences. However, current detection methodologies…
Deep Learning Approach for Large-Scale, Real-Time Quantification of Green Fluorescent Protein-Labeled Biological Samples in Microreactors
Yuanyuan Wei, Sai Mu Dalike Abaxi, Nawaz Mehmood +7
Absolute quantification of biological samples entails determining expression levels in precise numerical copies, offering enhanced accuracy and superior performance for rare templa…