3 papers
stat.ME2026
Robust Mendelian Randomization Estimation using Weighted Quantile Regression
Julien St-Pierre, Archer Y. Yang, Mireille E. Schnitzer +1
In Mendelian randomization (MR) studies, genetic variants are used as instrumental variables (IVs) to investigate causal relationships between exposures and outcomes based on obser…
stat.ME2025
Penalized generalized linear mixed models for longitudinal outcomes in genetic association studies
Julien St-Pierre, Sahir Rai Bhatnagar, Massimiliano Orri +3
This work is motivated by analyses of longitudinal data collected from participants in the Quebec Longitudinal Study of Child Development (QLSCD) and the Quebec Newborn Twin Study…
stat.ME2023
Hierarchical selection of genetic and gene by environment interaction effects in high-dimensional mixed models
Julien St-Pierre, Karim Oualkacha
Interactions between genes and environmental factors may play a key role in the etiology of many common disorders. Several regularized generalized linear models (GLMs) have been pr…