activity
20222026
most citedImaging-based representation and stratification of intra-tumor Heterogeneity via tree-edit distance

11 citations · 12 across the 6 of their papers we have counts for

collaborators

6 papers

stat.CO2026

Penalized Likelihood Optimization for Adaptive Neighborhood Clustering in Time-to-Event Data with Group-Level Heterogeneity

Alessandra Ragni, Lara Cavinato, Francesca Ieva

The identification of patient subgroups with comparable event-risk dynamics plays a key role in supporting informed decision-making in clinical research. In such settings, it is im…

stat.CO2025

TimeDepFrail: Time-Dependent Shared Frailty Cox Models in R

Alessandra Ragni, Giulia Romani, Chiara Masci

This paper introduces TimeDepFrail, an R package designed to implement time-varying shared frailty models by extending the traditional shared frailty Cox model to allow the frailty…

stat.ME2024

Nonparametric estimation of the Patient Weighted While-Alive Estimand

Alessandra Ragni, Torben Martinussen, Thomas Scheike

In clinical trials with recurrent events, such as repeated hospitalizations terminating with death, it is important to consider the patient events overall history for a thorough as…

stat.AP2024★ 1 cited

Analysis of Higher Education Dropouts Dynamics through Multilevel Functional Decomposition of Recurrent Events in Counting Processes

Alessandra Ragni, Chiara Masci, Anna Maria Paganoni

This paper analyzes the dynamics of higher education dropouts through an innovative approach that integrates recurrent events modeling and point process theory with functional data…

stat.ME2023

Clustering Hierarchies via a Semi-Parametric Generalized Linear Mixed Model: a statistical significance-based approach

Alessandra Ragni, Chiara Masci, Francesca Ieva +1

We introduce a novel statistical significance-based approach for clustering hierarchical data using semi-parametric linear mixed-effects models designed for responses with laws in…

stat.ME2022★ 11 cited

Imaging-based representation and stratification of intra-tumor Heterogeneity via tree-edit distance

Lara Cavinato, Matteo Pegoraro, Alessandra Ragni +3

Personalized medicine is the future of medical practice. In oncology, tumor heterogeneity assessment represents a pivotal step for effective treatment planning and prognosis predic…