27 citations · 37 across the 3 of their papers we have counts for
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q-bio.BM2013★ 27 cited
Helices 2 and 3 are the initiation sites in the PrPc -> PrPsc transition
Jie Chen, Devarajan Thirumalai
It is established that prion protein is the sole causative agent in a number of diseases in humans and animals. However, the nature of conformational changes that the normal cellul…
q-bio.BM2007
Allosteric communication in Dihydrofolate Reductase: Signaling network and pathways for closed to occluded transition and back
Jie Chen, Ruxandra I. Dima, D. Thirumalai
E. Coli. dihydrofolate reductase (DHFR) undergoes conformational transitions between the closed (CS) and occluded (OS) states which, respectively, describe whether the active site…