Towards Reliable WMH Segmentation under Domain Shift: An Application Study using Maximum Entropy Regularization to Improve Uncertainty Estimation

Franco Matzkin, Agostina Larrazabal, Diego H Milone +2

Accurate segmentation of white matter hyperintensities (WMH) is crucial for clinical decision-making, particularly in the context of multiple sclerosis. However, domain shifts, suc…