activity
20232026
most citedUnderstanding metric-related pitfalls in image analysis validation

204 citations · 209 across the 10 of their papers we have counts for

collaborators

11 papers

cs.LG2026

Collapsibility of Performance Metrics in Clinical Predictive AI

João Matos, Ben Van Calster, Richard D. Riley +2

Background: Population level assessments of predictive artificial intelligence (AI) can conceal performance disparities across subgroups. Fairness evaluations commonly rely on perf…

stat.ME2026

Incorporating Missing Data Considerations into Sample Size Calculations for Developing Clinical Prediction Models

Glen P. Martin, Sian Bladon, Rebecca Whittle +3

Clinical prediction models must be developed using sufficiently large datasets to minimise overfitting and ensure robust predictive performance. Existing sample size calculations a…

cs.CY2025

Code Sharing in Healthcare Research: A Practical Guide and Recommendations for Good Practice

Lukas Hughes-Noehrer, Matthew J Parkes, Andrew Stewart +8

As computational analysis becomes increasingly more complex in health research, transparent sharing of analytical code is vital for reproducibility and trust. This practical guide,…

stat.ME2025

Sequential sample size calculations and learning curves safeguard the robust development of a clinical prediction model for individuals

Amardeep Legha, Joie Ensor, Rebecca Whittle +7

When prospectively developing a new clinical prediction model (CPM), fixed sample size calculations are typically conducted before data collection based on sensible assumptions. Bu…

stat.ME2025

A decomposition of Fisher's information to inform sample size for developing or updating fair and precise clinical prediction models -- Part 3: continuous outcomes

Rebecca Whittle, Richard D Riley, Lucinda Archer +4

Clinical prediction models enable healthcare professionals to estimate individual outcomes using patient characteristics. Current sample size guidelines for developing or updating…

cs.LG2025★ 1 cited

Critical Appraisal of Fairness Metrics in Clinical Predictive AI

João Matos, Ben Van Calster, Leo Anthony Celi +6

Predictive artificial intelligence (AI) offers an opportunity to improve clinical practice and patient outcomes, but risks perpetuating biases if fairness is inadequately addressed…

stat.ME2025★ 1 cited

A general sample size framework for developing or updating a clinical prediction model

Richard D Riley, Rebecca Whittle, Mohsen Sadatsafavi +4

Aims: To propose a general sample size framework for developing or updating a clinical prediction model using any statistical or machine learning method, based on drawing samples f…

stat.ME2025

A decomposition of Fisher's information to inform sample size for developing fair and precise clinical prediction models -- Part 2: time-to-event outcomes

Richard D Riley, Gary S Collins, Lucinda Archer +9

Background: When developing a clinical prediction model using time-to-event data, previous research focuses on the sample size to minimise overfitting and precisely estimate the ov…

stat.ME2024★ 2 cited

A decomposition of Fisher's information to inform sample size for developing fair and precise clinical prediction models -- part 1: binary outcomes

Richard D Riley, Gary S Collins, Rebecca Whittle +11

When developing a clinical prediction model, the sample size of the development dataset is a key consideration. Small sample sizes lead to greater concerns of overfitting, instabil…

stat.ME2024★ 1 cited

Extended sample size calculations for evaluation of prediction models using a threshold for classification

Rebecca Whittle, Joie Ensor, Lucinda Archer +10

When evaluating the performance of a model for individualised risk prediction, the sample size needs to be large enough to precisely estimate the performance measures of interest.…

cs.CV2023★ 204 cited

Understanding metric-related pitfalls in image analysis validation

Annika Reinke, Minu D. Tizabi, Michael Baumgartner +75

Validation metrics are key for the reliable tracking of scientific progress and for bridging the current chasm between artificial intelligence (AI) research and its translation int…