2 citations · 5 across the 5 of their papers we have counts for
5 papers
Detection of an ancient principle and an elegant solution to the protein classification problem
Ashok Palaniappan
This work is concerned with the development of a well-founded, theoretically justified, and least complicated metric for the classification of proteins with reference to enzymes. A…
Fourier Analysis of Biological Evolution: Concept of Selection Moment
Ashok Palaniappan
Secondary structure elements of many protein families exhibit differential conservation on their opposing faces. Amphipathic helices and beta-sheets by definition possess this prop…
A robust methodology for inferring physiology of a protein family: application to K+-ion channel family
Ashok Palaniappan
We are interested in the subtle variations of function among the members of a protein family. A protein family is usually subdivided into subfamilies based on functional difference…
Evolutionary Analysis of Biological Excitability
Ashok Palaniappan, Eric Jakobsson
Excitability is an attribute of life, and is a driving force in the descent of complexity. Cellular electrical activity as realized by membrane proteins that act as either channels…
A Surprising Clarification of the Mechanism of Ion-channel Voltage-Gating
Ashok Palaniappan
An intense controversy has surrounded the mechanism of voltage-gating in ion channels. We interpreted the two leading models of voltage-gating with respect to the thermodynamic ene…