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DeCo-MIL: Debiased Counterfactual Reasoning for Long-Tailed Whole Slide Image Analysis
Xiaoxiao Li, Xitong Ling, Jiawen Li +6
Multiple instance learning (MIL) is widely used for weakly supervised whole slide image (WSI) analysis. However, under long-tailed distributions, MIL-based WSI analysis faces a nes…
Pretraining Multiple Instance Learning Networks with Multi-Teacher Distillation from Pathology Slide Foundation Models
Mingxi Fu, Jiawen Li, Renao Yan +4
Multiple instance learning (MIL) has become the main paradigm for whole-slide image (WSI) analysis in computational pathology. However, existing MIL aggregators are still typically…
ALICE: Learning a General-Purpose Pathology Foundation Model from Vision, Vision-Language, and Slide-Level Experts
Jiawen Li, Tian Guan, Huijuan Shi +5
Foundation models are reshaping computational pathology, yet their capabilities remain shaped by pretraining objectives, data sources, and spatial scales, fragmenting complementary…
SlideCheck: Guiding Self-Supervised Pretraining of Pathology Foundation Models via Dataset Distributions
Mingyi He, Xinyi Guo, Xitong Ling +7
Pathology foundation models are pretrained on large streams of WSI-derived patches, while supervision during data construction is often slide-level, sparse, or heterogeneous. This…
Is Class Signal Clustered or Routed in Task-Induced Implicit Neural Representation Weight Spaces?
Xinyi Guo, Mingyi He, Haobin Ding +7
Implicit neural representations (INRs) encode images as neural-network weights, making image classification a problem of weight-space classifiability. A natural geometric hypothesi…
Beyond ViT Tokens: Masked-Diffusion Pretrained Convolutional Pathology Foundation Model for Cell-Level Dense Prediction
Weiming Chen, Xitong Ling, Zhenyang Cai +5
Cell-level dense prediction is central to computational pathology, but remains challenging due to fine-grained histological structures, strong domain shifts, and costly dense annot…
A Digital Pathology Resource for Liver Cancer Quantification with Datasets, Benchmarks, and Tools
Ying Xiao, Shimiao Tang, Xitong Ling +11
Liver cancer, especially hepatocellular carcinoma (HCC), imposes a substantial global disease burden. Accurate diagnosis and prognostic assessment directly influence treatment sele…
HookMIL: Revisiting Context Modeling in Multiple Instance Learning for Computational Pathology
Xitong Ling, Minxi Ouyang, Xiaoxiao Li +7
Multiple Instance Learning (MIL) has enabled weakly supervised analysis of whole-slide images (WSIs) in computational pathology. However, traditional MIL approaches often lose cruc…
From Generic to Specialized: A Subspecialty Diagnostic System Powered by Self-Supervised Learning for Cervical Histopathology
Yizhi Wang, Li Chen, Qiang Huang +24
Cervical cancer remains a major malignancy, necessitating extensive and complex histopathological assessments and comprehensive support tools. Although deep learning shows promise,…
Deformable Attention Graph Representation Learning for Histopathology Whole Slide Image Analysis
Mingxi Fu, Xitong Ling, Yuxuan Chen +6
Accurate classification of Whole Slide Images (WSIs) and Regions of Interest (ROIs) is a fundamental challenge in computational pathology. While mainstream approaches often adopt M…
Cross-Modal Prototype Allocation: Unsupervised Slide Representation Learning via Patch-Text Contrast in Computational Pathology
Yuxuan Chen, Jiawen Li, Jiali Hu +4
With the rapid advancement of pathology foundation models (FMs), the representation learning of whole slide images (WSIs) attracts increasing attention. Existing studies develop hi…
Multimodal Distillation-Driven Ensemble Learning for Long-Tailed Histopathology Whole Slide Images Analysis
Xitong Ling, Yifeng Ping, Jiawen Li +8
Multiple Instance Learning (MIL) plays a significant role in computational pathology, enabling weakly supervised analysis of Whole Slide Image (WSI) datasets. The field of WSI anal…
Can We Simplify Slide-level Fine-tuning of Pathology Foundation Models?
Jiawen Li, Jiali Hu, Qiehe Sun +6
The emergence of foundation models in computational pathology has transformed histopathological image analysis, with whole slide imaging (WSI) diagnosis being a core application. T…
Dynamic Hypergraph Representation for Bone Metastasis Cancer Analysis
Yuxuan Chen, Jiawen Li, Huijuan Shi +5
Bone metastasis analysis is a significant challenge in pathology and plays a critical role in determining patient quality of life and treatment strategies. The microenvironment and…
Diagnostic Text-guided Representation Learning in Hierarchical Classification for Pathological Whole Slide Image
Jiawen Li, Qiehe Sun, Renao Yan +7
With the development of digital imaging in medical microscopy, artificial intelligent-based analysis of pathological whole slide images (WSIs) provides a powerful tool for cancer d…
RetMIL: Retentive Multiple Instance Learning for Histopathological Whole Slide Image Classification
Hongbo Chu, Qiehe Sun, Jiawen Li +5
Histopathological whole slide image (WSI) analysis with deep learning has become a research focus in computational pathology. The current paradigm is mainly based on multiple insta…
Dynamic Graph Representation with Knowledge-aware Attention for Histopathology Whole Slide Image Analysis
Jiawen Li, Yuxuan Chen, Hongbo Chu +4
Histopathological whole slide images (WSIs) classification has become a foundation task in medical microscopic imaging processing. Prevailing approaches involve learning WSIs as in…