3 papers
q-bio.MN2007
The p53-MDM2 network: from oscillations to apoptosis
Indrani Bose, Bhaswar Ghosh
The p53 protein is well-known for its tumour suppressor function. The p53-MDM2 negative feedback loop constitutes the core module of a network of regulatory interactions activated…
q-bio.MN2005
Gene Copy Number and Cell Cycle Arrest
Bhaswar Ghosh, Indrani Bose
The cell cycle is an orderly sequence of events which ultimately lead to the division of a single cell into two daughter cells. In the case of DNA damage by radiation or chemicals,…
q-bio.MN2004
Noise Characteristics of Feed Forward Loops
Bhaswar Ghosh, Rajesh Karmakar, Indrani Bose
A prominent feature of gene transcription regulatory networks is the presence in large numbers of motifs, i.e, patterns of interconnection, in the networks. One such motif is the f…