27 citations · 29 across the 11 of their papers we have counts for
14 papers
Amplifying gene expression sensitivity by surface condensation on DNA
Tarek Tohme, Henry Alston, Jacqueline Janssen +2
Condensation of proteins on DNA is a central aspect of genome organisation, and has been proposed as a mechanism of gene regulation in eukaryotes, notably by mediating the action o…
Approach to Steady-State in Nested Resetting Processes
Callum Britton, Ben Le Jeune, Henry Alston +2
We characterise the approach to nonequilibrium steady state in nested resetting processes by deriving accumulation times for the system, which quantify the effective first-passage…
Finite-Time Optimal Control by Noisy Traps
Luca Cocconi, Henry Alston, Thibault Bertrand
The optimal control of passive systems in equilibrium typically favours quasistatic (infinite-time) protocols. We show that a breakdown of quasistatic optimality occurs when the co…
Neutralization titers reveal the structure of polyclonal antibody responses
Henry Alston, Thierry Mora, Aleksandra M. Walczak
The composition of a polyclonal antibody response is hard to measure experimentally but contains vital information about the robustness of immunity. Here, we argue that the statist…
Controlling the Glass Transition through Active Fluctuating Interactions
Emir Sezik, Henry Alston, Thibault Bertrand
Fluctuating pairwise interactions are understood to drive fluid-like states in dense biological systems. These states find a broad range of functionalities, such as directing growt…
Stochastic Forces Enhance Tracer Diffusion in Non-motile Active Matter
Henry Alston, Raphael Voituriez, Thibault Bertrand
Stochasticity is a defining feature of the pairwise forces governing interactions in biological systems-from molecular motors to cell-cell adhesion-yet its consequences on large-sc…
Conditional splitting probabilities for hidden-state inference in drift-diffusive processes
Emir Sezik, Jacob Knight, Henry Alston +4
Splitting probabilities quantify the likelihood of particular outcomes out of a set of mutually-exclusive possibilities for stochastic processes and play a central role in first-pa…
Theoretical limits for sensing through phase separation
Henry Alston, Mason Rouches, Arvind Murugan +2
Biomolecular condensates form on timescales of seconds in cells upon environmental or compositional changes. Condensate formation is thus argued to act as a mechanism for sensing s…
Nested Stochastic Resetting: Nonequilibrium Steady-states and Exact Correlations
Henry Alston, Callum Britton, Thibault Bertrand
Stochastic resetting breaks detailed balance and drives the formation of nonequilibrium steady states . Here, we consider a chain of diffusive processes that interact unil…
The OU process: Characterising dissipative confinement in noisy traps
Luca Cocconi, Henry Alston, Jacopo Romano +1
The Ornstein-Uhlenbeck (OU) process describes the dynamics of Brownian particles in a confining harmonic potential, thereby constituting the paradigmatic model of overdamped, mean-…
Boosting macroscopic diffusion with local resetting
Henry Alston, Thibault Bertrand
Stochastic interactions generically enhance self-diffusivity in living and biological systems, e.g. optimizing navigation strategies and controlling material properties of cellular…
Irreversibility across a nonreciprocal -symmetry-breaking phase transition
Henry Alston, Luca Cocconi, Thibault Bertrand
Nonreciprocal interactions are commonplace in continuum-level descriptions of both biological and synthetic active matter, yet studies addressing their implications for time-revers…
Active Bound States Arise From Transiently Nonreciprocal Pair Interactions
Luca Cocconi, Henry Alston, Thibault Bertrand
Static nonreciprocal forces between particles generically drive persistent motion reminiscent of self-propulsion. Here, we demonstrate that reciprocity-breaking fluctuations about…
Non-equilibrium thermodynamics of diffusion in fluctuating potentials
Henry Alston, Luca Cocconi, Thibault Bertrand
A positive rate of entropy production at steady state is a distinctive feature of truly non-equilibrium processes. Exact results, while being often limited to simple models, offer…