5 papers
Large-Scale Pre-training Enables Multimodal AI Differentiation of Radiation Necrosis from Brain Metastasis Progression on Routine MRI
Ahmed Gomaa, Annette Schwarz, Ludwig Singer +23
Background: Differentiating radiation necrosis (RN) from tumor progression after stereotactic radiosurgery (SRS) remains a critical challenge in brain metastases. While histopathol…
Benchmarking GPT-5 in Radiation Oncology: Measurable Gains, but Persistent Need for Expert Oversight
Ugur Dinc, Jibak Sarkar, Philipp Schubert +16
Introduction: Large language models (LLM) have shown great potential in clinical decision support. GPT-5 is a novel LLM system that has been specifically marketed towards oncology…
A Self-supervised Multimodal Deep Learning Approach to Differentiate Post-radiotherapy Progression from Pseudoprogression in Glioblastoma
Ahmed Gomaa, Yixing Huang, Pluvio Stephan +19
Accurate differentiation of pseudoprogression (PsP) from True Progression (TP) following radiotherapy (RT) in glioblastoma (GBM) patients is crucial for optimal treatment planning.…
Comprehensive Multimodal Deep Learning Survival Prediction Enabled by a Transformer Architecture: A Multicenter Study in Glioblastoma
Ahmed Gomaa, Yixing Huang, Amr Hagag +16
Background: This research aims to improve glioblastoma survival prediction by integrating MR images, clinical and molecular-pathologic data in a transformer-based deep learning mod…
Complex-valued neural networks to speed-up MR Thermometry during Hyperthermia using Fourier PD and PDUNet
Rupali Khatun, Soumick Chatterjee, Christoph Bert +6
Hyperthermia (HT) in combination with radio- and/or chemotherapy has become an accepted cancer treatment for distinct solid tumour entities. In HT, tumour tissue is exogenously hea…