6 citations · 8 across the 11 of their papers we have counts for
4 papers · 1 filter
Optimal weighted tests for replication studies and the two-trials rule
David S. Robertson, Thomas Jaki
Replication studies for scientific research are an important part of ensuring the reliability and integrity of experimental findings. In the context of clinical trials, the concept…
A comparison of approaches to incorporate patient-selected and patient-ranked outcomes in clinical trials
David S. Robertson, Thomas Jaki
A key aspect of patient-focused drug development is identifying and measuring outcomes that are important to patients in clinical trials. Many medical conditions affect multiple sy…
A Bayesian Additive Regression Trees Model for zero and one inflated data for Predicting Individual Treatment Effects in Alcohol Use Disorder Trials
Pamela Solano, M Lee Van Horn, Kyle Walters +4
Alcohol Use Disorder (AUD) treatment presents high individual-level heterogeneity, with outcomes ranging from complete abstinence to persistent heavy drinking. This variability-dri…
Joint TITE-CRM for Dual Agent Dose Finding Studies
Helen Barnett, Oliver Boix, Dimitris Kontos +1
Dual agent dose-finding trials study the effect of a combination of more than one agent, where the objective is to find the Maximum Tolerated Dose Combination (MTC), the combinatio…