most citedHoloHisto: End-to-end Gigapixel WSI Segmentation with 4K Resolution Sequential Tokenization

4 citations · 8 across the 18 of their papers we have counts for

collaborators

19 papers

cs.CV2025

How Close Are We? Limitations and Progress of AI Models in Banff Lesion Scoring

Yanfan Zhu, Juming Xiong, Ruining Deng +7

The Banff Classification provides the global standard for evaluating renal transplant biopsies, yet its semi-quantitative nature, complex criteria, and inter-observer variability p…

q-bio.QM2025

Evaluating New AI Cell Foundation Models on Challenging Kidney Pathology Cases Unaddressed by Previous Foundation Models

Runchen Wang, Junlin Guo, Siqi Lu +12

Accurate cell nuclei segmentation is critical for downstream tasks in kidney pathology and remains a major challenge due to the morphological diversity and imaging variability of r…

cs.CV2025

Img2ST-Net: Efficient High-Resolution Spatial Omics Prediction from Whole Slide Histology Images via Fully Convolutional Image-to-Image Learning

Junchao Zhu, Ruining Deng, Junlin Guo +10

Recent advances in multi-modal AI have demonstrated promising potential for generating the currently expensive spatial transcriptomics (ST) data directly from routine histology ima…

cs.CV2025

ZeroReg3D: A Zero-shot Registration Pipeline for 3D Consecutive Histopathology Image Reconstruction

Juming Xiong, Ruining Deng, Jialin Yue +10

Histological analysis plays a crucial role in understanding tissue structure and pathology. While recent advancements in registration methods have improved 2D histological analysis…

eess.IV2025

IRS: Incremental Relationship-guided Segmentation for Digital Pathology

Ruining Deng, Junchao Zhu, Juming Xiong +14

Continual learning is rapidly emerging as a key focus in computer vision, aiming to develop AI systems capable of continuous improvement, thereby enhancing their value and practica…

cs.CV2025

CASC-AI: Consensus-aware Self-corrective Learning for Noise Cell Segmentation

Ruining Deng, Yihe Yang, David J. Pisapia +15

Multi-class cell segmentation in high-resolution gigapixel whole slide images (WSIs) is crucial for various clinical applications. However, training such models typically requires…

cs.CV2025

MagNet: Multi-Level Attention Graph Network for Predicting High-Resolution Spatial Transcriptomics

Junchao Zhu, Ruining Deng, Tianyuan Yao +12

The rapid development of spatial transcriptomics (ST) offers new opportunities to explore the gene expression patterns within the spatial microenvironment. Current research integra…

cs.CV2025

KPIs 2024 Challenge: Advancing Glomerular Segmentation from Patch- to Slide-Level

Ruining Deng, Tianyuan Yao, Yucheng Tang +44

Chronic kidney disease (CKD) is a major global health issue, affecting over 10% of the population and causing significant mortality. While kidney biopsy remains the gold standard f…

eess.IV2025

PySpatial: A High-Speed Whole Slide Image Pathomics Toolkit

Yuechen Yang, Yu Wang, Tianyuan Yao +5

Whole Slide Image (WSI) analysis plays a crucial role in modern digital pathology, enabling large-scale feature extraction from tissue samples. However, traditional feature extract…

cs.CV2024★ 1 cited

ASIGN: An Anatomy-aware Spatial Imputation Graphic Network for 3D Spatial Transcriptomics

Junchao Zhu, Ruining Deng, Tianyuan Yao +9

Spatial transcriptomics (ST) is an emerging technology that enables medical computer vision scientists to automatically interpret the molecular profiles underlying morphological fe…

eess.IV2024

Glo-In-One-v2: Holistic Identification of Glomerular Cells, Tissues, and Lesions in Human and Mouse Histopathology

Lining Yu, Mengmeng Yin, Ruining Deng +9

Segmenting glomerular intraglomerular tissue and lesions traditionally depends on detailed morphological evaluations by expert nephropathologists, a labor-intensive process suscept…

cs.CV2024

GloFinder: AI-empowered QuPath Plugin for WSI-level Glomerular Detection, Visualization, and Curation

Jialin Yue, Tianyuan Yao, Ruining Deng +7

Artificial intelligence (AI) has demonstrated significant success in automating the detection of glomeruli, the key functional units of the kidney, from whole slide images (WSIs) i…

cs.CV2024★ 1 cited

Evaluating Cell AI Foundation Models in Kidney Pathology with Human-in-the-Loop Enrichment

Junlin Guo, Siqi Lu, Can Cui +14

Training AI foundation models has emerged as a promising large-scale learning approach for addressing real-world healthcare challenges, including digital pathology. While many of t…

eess.IV2024

Cross-Species Data Integration for Enhanced Layer Segmentation in Kidney Pathology

Junchao Zhu, Mengmeng Yin, Ruining Deng +6

Accurate delineation of the boundaries between the renal cortex and medulla is crucial for subsequent functional structural analysis and disease diagnosis. Training high-quality de…

eess.IV2024

Assessment of Cell Nuclei AI Foundation Models in Kidney Pathology

Junlin Guo, Siqi Lu, Can Cui +14

Cell nuclei instance segmentation is a crucial task in digital kidney pathology. Traditional automatic segmentation methods often lack generalizability when applied to unseen datas…

eess.IV2024★ 4 cited

HoloHisto: End-to-end Gigapixel WSI Segmentation with 4K Resolution Sequential Tokenization

Yucheng Tang, Yufan He, Vishwesh Nath +11

In digital pathology, the traditional method for deep learning-based image segmentation typically involves a two-stage process: initially segmenting high-resolution whole slide ima…

eess.IV2024★ 1 cited

GLAM: Glomeruli Segmentation for Human Pathological Lesions using Adapted Mouse Model

Lining Yu, Mengmeng Yin, Ruining Deng +9

Moving from animal models to human applications in preclinical research encompasses a broad spectrum of disciplines in medical science. A fundamental element in the development of…

eess.IV2024

HATs: Hierarchical Adaptive Taxonomy Segmentation for Panoramic Pathology Image Analysis

Ruining Deng, Quan Liu, Can Cui +10

Panoramic image segmentation in computational pathology presents a remarkable challenge due to the morphologically complex and variably scaled anatomy. For instance, the intricate…

eess.IV2024★ 1 cited

PrPSeg: Universal Proposition Learning for Panoramic Renal Pathology Segmentation

Ruining Deng, Quan Liu, Can Cui +11

Understanding the anatomy of renal pathology is crucial for advancing disease diagnostics, treatment evaluation, and clinical research. The complex kidney system comprises various…