most citedDrugImproverGPT: A Large Language Model for Drug Optimization with Fine-Tuning via Structured Policy Optimization

1 citations · 1 across the 3 of their papers we have counts for

collaborators

5 papers

stat.ML2025

Quantile-Optimal Policy Learning under Unmeasured Confounding

Zhongren Chen, Siyu Chen, Zhengling Qi +2

We study quantile-optimal policy learning where the goal is to find a policy whose reward distribution has the largest -quantile for some . We focus on the offline…

math.ST2025

An Optimized Franz-Parisi Criterion and its Equivalence with SQ Lower Bounds

Siyu Chen, Theodor Misiakiewicz, Ilias Zadik +1

Bandeira et al. (2022) introduced the Franz-Parisi (FP) criterion for characterizing the computational hard phases in statistical detection problems. The FP criterion, based on an…

cs.CL2025

Penrose Tiled Low-Rank Compression and Section-Wise Q&A Fine-Tuning: A General Framework for Domain-Specific Large Language Model Adaptation

Chuan-Wei Kuo, Siyu Chen, Chenqi Yan +1

Large language models (LLMs) hold great promise for specialized scientific domains such as materials science, yet adapting them efficiently and accurately to domain-specific knowle…

cs.LG20251 cited

DrugImproverGPT: A Large Language Model for Drug Optimization with Fine-Tuning via Structured Policy Optimization

Xuefeng Liu, Songhao Jiang, Siyu Chen +4

Finetuning a Large Language Model (LLM) is crucial for generating results towards specific objectives. This research delves into the realm of drug optimization and introduce a nove…

cs.LG2024

DrugAgent: Automating AI-aided Drug Discovery Programming through LLM Multi-Agent Collaboration

Sizhe Liu, Yizhou Lu, Siyu Chen +4

Recent progress in Large Language Models (LLMs) has drawn attention to their potential for accelerating drug discovery. However, a central problem remains: translating theoretical…