6 citations · 7 across the 6 of their papers we have counts for
4 papers · 1 filter
Extending Sequence Length is Not All You Need: Effective Integration of Multimodal Signals for Gene Expression Prediction
Zhao Yang, Yi Duan, Jiwei Zhu +3
Gene expression prediction, which predicts mRNA expression levels from DNA sequences, presents significant challenges. Previous works often focus on extending input sequence length…
D3LM: A Discrete DNA Diffusion Language Model for Bidirectional DNA Understanding and Generation
Zhao Yang, Hengchang Liu, Chuan Cao +1
Early DNA foundation models adopted BERT-style training, achieving good performance on DNA understanding tasks but lacking generative capabilities. Recent autoregressive models ena…
Regulatory DNA sequence Design with Reinforcement Learning
Zhao Yang, Bing Su, Chuan Cao +1
Cis-regulatory elements (CREs), such as promoters and enhancers, are relatively short DNA sequences that directly regulate gene expression. The fitness of CREs, measured by their a…
HybriDNA: A Hybrid Transformer-Mamba2 Long-Range DNA Language Model
Mingqian Ma, Guoqing Liu, Chuan Cao +12
Advances in natural language processing and large language models have sparked growing interest in modeling DNA, often referred to as the "language of life". However, DNA modeling…