23 citations · 54 across the 14 of their papers we have counts for
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cs.LG2023★ 1 cited
A framework for conditional diffusion modelling with applications in motif scaffolding for protein design
Kieran Didi, Francisco Vargas, Simon V Mathis +4
Many protein design applications, such as binder or enzyme design, require scaffolding a structural motif with high precision. Generative modelling paradigms based on denoising dif…
q-bio.BM2023★ 23 cited
Benchmarking Generated Poses: How Rational is Structure-based Drug Design with Generative Models?
Charles Harris, Kieran Didi, Arian R. Jamasb +4
Deep generative models for structure-based drug design (SBDD), where molecule generation is conditioned on a 3D protein pocket, have received considerable interest in recent years.…