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stat.ME2026
The INSIDE assumption under all positive coding: interpretation and partial empirical assessment
Fernando Pires Hartwig, George Davey Smith, Frank Dudbridge +1
Mendelian randomisation (MR) implemented through instrumental variable (IV) analysis is a popular strategy for strengthening causal inference in observational studies. A key assump…
stat.ME2026
Towards more plausible point-identifying assumptions in two-sample Mendelian randomization
Fernando Pires Hartwig, Neil Martin Davies, George Davey Smith
Two-sample Mendelian randomization (MR) is a widely used methodology in epidemiology. In two-sample MR, summary data (typically regression coefficients and standard errors) quantif…