117 citations · 239 across the 36 of their papers we have counts for
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A Retrospective Study on the Investigation of Potential Clinical Benefits of Online Adaptive Proton Therapy for Head and Neck Cancer
Chih-Wei Chang, Duncan Bohannon, Zhen Tian +6
Online adaptive proton therapy (APT) is an ideal solution theoretically, which however is challenging to proton clinics. Although multiple groups have been endeavoring to develop o…
Early in vivo Radiation Damage Quantification for Pediatric Craniospinal Irradiation Using Longitudinal MRI for Intensity Modulated Proton Therapy
Chih-Wei Chang, Matt Goette, Nadja Kadom +8
Purpose: Proton vertebral body sparing craniospinal irradiation (VBS CSI) treats the thecal sac while avoiding the anterior vertebral bodies in effort to reduce myelosuppression an…
Deep learning-based Fast Volumetric Image Generation for Image-guided Proton FLASH Radiotherapy
Chih-Wei Chang, Yang Lei, Tonghe Wang +7
Proton FLASH therapy leverages ultra-high dose-rate radiation to enhance the sparing of organs at risk without compromising tumor control probability. To prepare for the delivery o…
MRI-based Material Mass Density and Relative Stopping Power Estimation via Deep Learning for Proton Therapy
Yuan Gao, Chih-Wei Chang, Sagar Mandava +10
Magnetic Resonance Imaging (MRI) is increasingly incorporated into treatment planning, because of its superior soft tissue contrast used for tumor and soft tissue delineation versu…
Feasibility Study of Hybrid Inverse Planning with Transmission Beams and Single-energy Spread-out Bragg Peaks for Proton Flash Radiotherapy
Chaoqiong Ma, Xiaofeng Yang, Chih-Wei Chang +6
Ultra-high dose rate (FLASH) proton planning with only transmission beams (TBs) has limitations in normal tissue sparing. The single-energy spread-out Bragg peaks (SESOBPs) of FLAS…
Characterization of 250 MeV protons from Varian ProBeam pencil beam scanning system for FLASH radiation therapy
Serdar Charyyev, Chih-Wei Chang, Mingyao Zhu +3
Recently, shoot-through proton FLASH has been proposed where the highest energy is extracted from the cyclotron to maximize the dose rate (DR). Even though our proton pencil beam s…
Multimodal Imaging-based Material Mass Density Estimation for Proton Therapy Using Physics-Constrained Deep Learning
Chih-Wei Chang, Raanan Marants, Yuan Gao +7
Mapping computed tomography (CT) number to material property dominates the proton range uncertainty. This work aims to develop a physics-constrained deep learning-based multimodal…