67 citations · 91 across the 2 of their papers we have counts for
2 papers
q-bio.QM2008★ 67 cited
Inherent flexibility determines the transition mechanisms of the EF-hands of Calmodulin
Swarnendu Tripathi, John J. Portman
We explore how inherent flexibility of a protein molecule influences the mechanism controlling the kinetics of allosteric transitions using a variational model inspired from work i…
q-bio.QM2007★ 24 cited
Inherent flexibility and protein function: the open/closed conformational transition of the N-terminal domain of calmodulin
Swarnendu Tripathi, John J. Portman
The key to understanding a protein's function often lies in its conformational dynamics. We develop a coarse-grained variational model to investigate the interplay between structur…