161 citations · 283 across the 6 of their papers we have counts for
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q-bio.BM2010★ 30 cited
Protein-mediated DNA Loop Formation and Breakdown in a Fluctuating Environment
Yih-Fan Chen, J. N. Milstein, Jens-Christian Meiners
Living cells provide a fluctuating, out-of-equilibrium environment in which genes must coordinate cellular function. DNA looping, which is a common means of regulating transcriptio…
q-bio.BM2010
Femtonewton Forces Can Control Protein-Meditated DNA Looping
Yih-Fan Chen, J. N. Milstein, J. -C. Meiners
We show that minuscule entropic forces, on the order of 100 fN, can prevent the formation of DNA loops--a ubiquitous means of regulating the expression of genes. We observe a tenfo…