14 citations · 40 across the 17 of their papers we have counts for
21 papers
Modeling Cell Size Distribution with Heterogeneous Flux Balance Analysis
Michiel Busschaert, Florence H. Vermeire, Steffen Waldherr
For over two decades, Flux Balance Analysis (FBA) has been successfully used for predicting growth rates and intracellular reaction rates in microbiological metabolism. An aspect t…
COVRECON: Combining Genome-scale Metabolic Network Reconstruction and Data-driven Inverse Modeling to Reveal Changes in Metabolic Interaction Networks
Jiahang Li, Steffen Waldherr, Wolfram Weckwerth
One central goal of systems biology is to infer biochemical regulations from large-scale OMICS data. Many aspects of cellular physiology and organism phenotypes could be understood…
Numerical Gaussian process Kalman filtering for spatiotemporal systems
Armin Küper, Steffen Waldherr
We present a novel Kalman filter for spatiotemporal systems called the numerical Gaussian process Kalman filter (GPKF). Numerical Gaussian processes have recently been introduced a…
Numerical Gaussian process Kalman filtering
Armin Küper, Steffen Waldherr
In this manuscript we introduce numerical Gaussian process Kalman filtering (GPKF). Numerical Gaussian processes have recently been developed to simulate spatiotemporal models. The…
Dynamic Density Estimation in Heterogeneous Cell Populations
Armin Küper, Robert Dürr, Steffen Waldherr
Multicellular systems play a key role in bioprocess and biomedical engineering. Cell ensembles encountered in these setups show phenotypic variability like size and biochemical com…
Dynamic modeling of enzyme controlled metabolic networks using a receding time horizon
Henning Lindhorst, Alexandra-M. Reimers, Steffen Waldherr
Microorganisms have developed complex regulatory features controlling their reaction and internal adaptation to changing environments. When modeling these organisms we usually do n…