193 citations · 510 across the 6 of their papers we have counts for
6 papers
Folding of Pig Gastric Mucin Non-glycosylated Domains: A Discrete Molecular Dynamics Study
Brigita Urbanc, Bradley S. Turner, Rama Bansil
Mucin glycoprotein consist of tandem repeating glycosylated regions flanked by non-repetitive protein domains with little glycosylation. These non-repetitive domains are involved i…
Automated identification of neurons and their locations
Andrew Inglis, Luis Cruz, Dan L. Roe +3
Individual locations of many neuronal cell bodies (>10^4) are needed to enable statistically significant measurements of spatial organization within the brain such as nearest-neigh…
Role of electrostatic interactions in amyloid beta-protein (Abeta) oligomer formation: A discrete molecular dynamics study
Sijung Yun, Brigita Urbanc, Luis Cruz +3
Pathological folding and oligomer formation of the amyloid beta-protein (Abeta) are widely perceived as central to Alzheimer's disease (AD). Experimental approaches to study Abeta…
Solvent and mutation effects on the nucleation of amyloid -protein folding
Luis Cruz, Brigita Urbanc, Jose M. Borreguero +3
Experimental evidence suggests that the folding and aggregation of the amyloid -protein (A) into oligomers is a key pathogenetic event in Alzheimer's disease (AD). Inhibiting…
Molecular Dynamics Simulation of Amyloid Beta Dimer Formation
B. Urbanc, L. Cruz, F. Ding +5
Recent experiments with amyloid-beta (Abeta) peptide suggest that formation of toxic oligomers may be an important contribution to the onset of Alzheimer's disease. The toxicity of…
Discrete molecular dynamics simulations of peptide aggregation
S. Peng, F. Ding, B. Urbanc +4
We study the aggregation of peptides using the discrete molecular dynamics simulations. At temperatures above the alpha-helix melting temperature of a single peptide, the model pep…