91 citations · 91 across the 2 of their papers we have counts for
3 papers
Extrinsic noise driven phenotype switching in a self-regulating gene
Michael Assaf, Elijah Roberts, Zaida Luthey-Schulten +1
Due to inherent noise in intracellular networks cellular decisions can be random, so genetically identical cells can display different phenotypic behavior even in identical environ…
Determining the stability of genetic switches: explicitly accounting for mRNA noise
Michael Assaf, Elijah Roberts, Zaida Luthey-Schulten
Cells use genetic switches to shift between alternate gene expression states, e.g., to adapt to new environments or to follow a developmental pathway. Here, we study the dynamics o…
Extreme genetic code optimality from a molecular dynamics calculation of amino acid polar requirement
Thomas Butler, Nigel Goldenfeld, Damien Mathew +1
A molecular dynamics calculation of the amino acid polar requirement is presented and used to score the canonical genetic code. Monte Carlo simulation shows that this computational…