2 papers
stat.ME2026
A Bias-Corrected Two-Stage Approach for Joint Modelling of Multidimensional Longitudinal HRQoL and Survival Data
Hortense Doms, Philippe Lambert, Catherine Legrand
Health-related quality-of-life (HRQoL) outcomes are increasingly incorporated into oncology research to complement traditional survival endpoints by capturing patients' well-being…
stat.ME2025
Tutorial for Surrogate Endpoint Validation Using Joint modeling and Mediation Analysis
Quentin Le Coent, Virginie Rondeau, Catherine Legrand
The use of valid surrogate endpoints is an important stake in clinical research to help reduce both the duration and cost of a clinical trial and speed up the evaluation of interes…