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cs.CV2026
Rethinking Genomic Modeling Through Optical Character Recognition
Hongxin Xiang, Pengsen Ma, Yunkang Cao +4
Recent genomic foundation models largely adopt large language model architectures that treat DNA as a one-dimensional token sequence. However, exhaustive sequential reading is stru…
cs.CV2025
ImageDDI: Image-enhanced Molecular Motif Sequence Representation for Drug-Drug Interaction Prediction
Yuqin He, Tengfei Ma, Chaoyi Li +6
To mitigate the potential adverse health effects of simultaneous multi-drug use, including unexpected side effects and interactions, accurately identifying and predicting drug-drug…
cs.CV2024
MaskMol: Knowledge-guided Molecular Image Pre-Training Framework for Activity Cliffs
Zhixiang Cheng, Hongxin Xiang, Pengsen Ma +9
Activity cliffs, which refer to pairs of molecules that are structurally similar but show significant differences in their potency, can lead to model representation collapse and ma…