2 citations · 3 across the 4 of their papers we have counts for
5 papers
Multipath Adaptive Gated Bottleneck Latent ODE with Raman Data Fusion for Cell Culture Process Forecasting
Johnny Peng, Thanh Tung Khuat, Ellen Otte +2
Mammalian cell-culture processes underpin the manufacture of many biopharmaceuticals, yet keeping a run on track is hard: critical process parameters drift over days, and an off-sp…
Learning From Limited Data and Feedback for Cell Culture Process Monitoring: A Comparative Study
Johnny Peng, Thanh Tung Khuat, Ellen Otte +2
In cell culture bioprocessing, real-time batch process monitoring (BPM) refers to the continuous tracking and analysis of key process variables such as viable cell density, nutrien…
Lessons Learned from Deploying Adaptive Machine Learning Agents with Limited Data for Real-time Cell Culture Process Monitoring
Thanh Tung Khuat, Johnny Peng, Robert Bassett +2
This study explores the deployment of three machine learning (ML) approaches for real-time prediction of glucose, lactate, and ammonium concentrations in cell culture processes, us…
Uncertainty Quantification Using Ensemble Learning and Monte Carlo Sampling for Performance Prediction and Monitoring in Cell Culture Processes
Thanh Tung Khuat, Robert Bassett, Ellen Otte +1
Biopharmaceutical products, particularly monoclonal antibodies (mAbs), have gained prominence in the pharmaceutical market due to their high specificity and efficacy. As these prod…
Applications of Machine Learning in Biopharmaceutical Process Development and Manufacturing: Current Trends, Challenges, and Opportunities
Thanh Tung Khuat, Robert Bassett, Ellen Otte +2
While machine learning (ML) has made significant contributions to the biopharmaceutical field, its applications are still in the early stages in terms of providing direct support f…