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stat.ME2026
Sequential Supersaturated Screening Experiments
Songqiao Han, Kalliopi Mylona, Steven Gilmour +1
Supersaturated screening experiments study many candidate factors with few runs. The experimenter must first identify the active factors, then optimize the response. One-shot regul…
stat.ME2026
Factorial clinical trials in the presence and absence of plausible statistical interactions between treatment factors. A historical review of the methodological literature
Rebecca E. A. Walwyn, Pritaporn Kingkaew, Alan A. Montgomery +2
Factorial trials can be conducted when statistical interactions between two or more treatment factors are not anticipated, but also when they are. A k-in-1 factorial trial answers…
stat.ME2026
Orthogonal factorial designs for trials of therapist-delivered interventions: Randomising intervention-therapist combinations to patients
Rebecca EA Walwyn, Rosemary A Bailey, Arpan Singh +2
It is recognised that treatment-related clustering should be allowed for in the sample size and analyses of individually-randomised parallel-group trials that evaluate therapist-de…