17 citations · 32 across the 12 of their papers we have counts for
5 papers · 1 filter
Detecting adverse high-order drug interactions from individual case safety reports using computational statistics on disproportionality measures
Jules Bangard, Einar Holsbø, Kristian Svendsen +2
Adverse drug interactions are a critical concern in pharmacovigilance, as both clinical trials and spontaneous reporting systems often lack the breadth to detect complex drug inter…
Shrinkage estimation of rate statistics
Einar Holsbø, Vittorio Perduca
This paper presents a simple shrinkage estimator of rates based on Bayesian methods. Our focus is on crime rates as a motivating example. The estimator shrinks each town's observed…
Non-subjective power analysis to detect G*E interactions in Genome-Wide Association Studies in presence of confounding factor
Flora Alarcon, Vittorio Perduca, Gregory Nuel
It is generally acknowledged that most complex diseases are affected in part by interactions between genes and genes and/or between genes and environmental factors. Taking into acc…
Hidden Markov Model Applications in Change-Point Analysis
The Minh Luong, Vittorio Perduca, Gregory Nuel
The detection of change-points in heterogeneous sequences is a statistical challenge with many applications in fields such as finance, signal analysis and biology. A wide variety o…
Alternative Methods for H1 Simulations in Genome Wide Association Studies
Vittorio Perduca, Christine Sinoquet, Raphael Mourad +1
Assessing the statistical power to detect susceptibility variants plays a critical role in GWA studies both from the prospective and retrospective points of view. Power is empirica…