activity
20232026
most citedTissue Concepts: supervised foundation models in computational pathology

6 citations · 8 across the 12 of their papers we have counts for

collaborators

12 papers

cs.CV2026

DSA-CycleGAN: A Domain Shift Aware CycleGAN for Robust Multi-Stain Glomeruli Segmentation

Zeeshan Nisar, Friedrich Feuerhake, Thomas Lampert

A key challenge in segmentation in digital histopathology is inter- and intra-stain variations as it reduces model performance. Labelling each stain is expensive and time-consuming…

cs.CV2026

Tissue Classification and Whole-Slide Images Analysis via Modeling of the Tumor Microenvironment and Biological Pathways

Junzhuo Liu, Xuemei Du, Daniel Reisenbuchler +5

Automatic integration of whole slide images (WSIs) and gene expression profiles has demonstrated substantial potential in precision clinical diagnosis and cancer progression studie…

eess.IV2026

Explainable histomorphology-based survival prediction of glioblastoma, IDH-wildtype

Jan-Philipp Redlich, Friedrich Feuerhake, Stefan Nikolin +12

Glioblastoma, IDH-wildtype (GBM-IDHwt) is the most common malignant brain tumor. While histomorphology is a crucial component of GBM-IDHwt diagnosis, it is not further considered f…

cs.LG2025

Automatic Extraction of Rules for Generating Synthetic Patient Data From Real-World Population Data Using Glioblastoma as an Example

Arno Appenzeller, Nick Terzer, André Homeyer +10

The generation of synthetic data is a promising technology to make medical data available for secondary use in a privacy-compliant manner. A popular method for creating realistic p…

cs.CV2025

Spatial Transcriptomics Expression Prediction from Histopathology Based on Cross-Modal Mask Reconstruction and Contrastive Learning

Junzhuo Liu, Markus Eckstein, Zhixiang Wang +2

Spatial transcriptomics is a technology that captures gene expression levels at different spatial locations, widely used in tumor microenvironment analysis and molecular profiling…

cs.LG2025

HIEGNet: A Heterogenous Graph Neural Network Including the Immune Environment in Glomeruli Classification

Niklas Kormann, Masoud Ramuz, Zeeshan Nisar +6

Graph Neural Networks (GNNs) have recently been found to excel in histopathology. However, an important histopathological task, where GNNs have not been extensively explored, is th…

cs.CV2025

Attention-based Generative Latent Replay: A Continual Learning Approach for WSI Analysis

Pratibha Kumari, Daniel Reisenbüchler, Afshin Bozorgpour +3

Whole slide image (WSI) classification has emerged as a powerful tool in computational pathology, but remains constrained by domain shifts, e.g., due to different organs, diseases,…

cs.CV2024

Resource Efficient Multi-stain Kidney Glomeruli Segmentation via Self-supervision

Zeeshan Nisar, Friedrich Feuerhake, Thomas Lampert

Semantic segmentation under domain shift remains a fundamental challenge in computer vision, particularly when labelled training data is scarce. This challenge is particularly exem…

eess.IV2024

Continual Domain Incremental Learning for Privacy-aware Digital Pathology

Pratibha Kumari, Daniel Reisenbüchler, Lucas Luttner +3

In recent years, there has been remarkable progress in the field of digital pathology, driven by the ability to model complex tissue patterns using advanced deep-learning algorithm…

eess.IV2024★ 6 cited

Tissue Concepts: supervised foundation models in computational pathology

Till Nicke, Jan Raphael Schaefer, Henning Hoefener +4

Due to the increasing workload of pathologists, the need for automation to support diagnostic tasks and quantitative biomarker evaluation is becoming more and more apparent. Founda…

eess.IV2024

Unsupervised Latent Stain Adaptation for Computational Pathology

Daniel Reisenbüchler, Lucas Luttner, Nadine S. Schaadt +2

In computational pathology, deep learning (DL) models for tasks such as segmentation or tissue classification are known to suffer from domain shifts due to different staining techn…

cs.CV2023★ 2 cited

Overcoming Data Scarcity in Biomedical Imaging with a Foundational Multi-Task Model

Raphael Schäfer, Till Nicke, Henning Höfener +6

Foundational models, pretrained on a large scale, have demonstrated substantial success across non-medical domains. However, training these models typically requires large, compreh…