3 papers
q-bio.BM2020
Recognition of potential Covid-19 drug treatments through the study of existing protein-drug and protein-protein structures: an analysis of kinetically active residues
Ognjen Perišić
We report the results of our study of approved drugs as potential treatments for COVID 19, based on the application of various bioinformatics predictive methods. The drugs studied…
q-bio.BM2016
Heterodimer binding scaffolds recognition via the analysis of kinetically hot residues
Ognjen Perišić
Physical interactions between proteins are often difficult to decipher. The aim of this paper is to present an algorithm designed to recognize binding patches and supporting struct…
cond-mat.stat-mech2007
Efficient free energy profile reconstruction using adaptive stochastic perturbation protocols
Ognjen Perisic, Hui Lu
Application of Jarzynski nonequilibrium work relation to free energy calculation is limited by the very slow convergence of the estimate when dissipation is high. We present a nove…