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20242026
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physics.med-ph2025

Objective Task-based Evaluation of Quantitative Medical Imaging Methods: Emerging Frameworks and Future Directions

Yan Liu, Huitian Xia, Nancy A. Obuchowski +4

Quantitative imaging (QI) is demonstrating strong promise across multiple clinical applications. For clinical translation of QI methods, objective evaluation on clinically relevant…

physics.med-ph2025

ISIT-GEN: An in silico imaging trial to assess the inter-scanner generalizability of CTLESS for myocardial perfusion SPECT on defect-detection task

Zitong Yu, Nu Ri Choi, Zezhang Yang +3

A recently proposed scatter-window and deep learning-based attenuation compensation (AC) method for myocardial perfusion imaging (MPI) by single-photon emission computed tomography…

physics.med-ph2024

CTLESS: A scatter-window projection and deep learning-based transmission-less attenuation compensation method for myocardial perfusion SPECT

Zitong Yu, Md Ashequr Rahman, Craig K. Abbey +4

Attenuation compensation (AC), while being beneficial for visual-interpretation tasks in myocardial perfusion imaging (MPI) by SPECT, typically requires the availability of a separ…

physics.med-ph2024

Can patient-specific acquisition protocol improve performance on defect detection task in myocardial perfusion SPECT?

Nu Ri Choi, Md Ashequr Rahman, Zitong Yu +2

Myocardial perfusion imaging using single-photon emission computed tomography (SPECT), or myocardial perfusion SPECT (MPS) is a widely used clinical imaging modality for the diagno…