activity
20222026
most citedDeep Learning in Spatially Resolved Transcriptomics: A Comprehensive Technical View

9 citations · 9 across the 13 of their papers we have counts for

collaborators

15 papers

q-bio.GN2026

Large Language Model Agents for Evidence Based Genetic Disease Severity Classification

Tohid Ghasemnejad, Ahmadreza Argha, Mark Grosser +7

Disease severity classification for genetic conditions is subjective and labor-intensive, creating bottlenecks in genomic screening, where commercial panels vary widely in size and…

q-bio.GN2026

Harmonised benchmarking of foundation models for single-cell and spatial transcriptomics reveals context-dependent generalisation

Sally Chen, Roxana Zahedi, Lucy Chhuo +12

Single-cell and spatial foundation models promise transferable biological representations, yet their generality remains largely untested across modalities, biological domains and a…

q-bio.GN2026

Transcriptomic Models for Immunotherapy Response Prediction Show Limited Cross-cohort Generalisability

Yuheng Liang, Lucy Chhuo, Ahmadreza Argha +9

Immune checkpoint inhibitors (ICIs) have transformed cancer therapy; yet substantial proportion of patients exhibit intrinsic or acquired resistance, making accurate pre-treatment…

cs.AI2026

Beyond Quantity: Trajectory Diversity Scaling for Code Agents

Guhong Chen, Chenghao Sun, Cheng Fu +16

As code large language models (LLMs) evolve into tool-interactive agents via the Model Context Protocol (MCP), their generalization is increasingly limited by low-quality synthetic…

cs.AI2025

RxSafeBench: Identifying Medication Safety Issues of Large Language Models in Simulated Consultation

Jiahao Zhao, Luxin Xu, Minghuan Tan +4

Numerous medical systems powered by Large Language Models (LLMs) have achieved remarkable progress in diverse healthcare tasks. However, research on their medication safety remains…

cs.AI2025

Structuring Reasoning for Complex Rules Beyond Flat Representations

Zhihao Yang, Ancheng Xu, Jingpeng Li +11

Large language models (LLMs) face significant challenges when processing complex rule systems, as they typically treat interdependent rules as unstructured textual data rather than…

q-bio.GN2025

SemanticST: Spatially Informed Semantic Graph Learning for Clustering, Integration, and Scalable Analysis of Spatial Transcriptomics

Roxana Zahedi, Ahmadreza Argha, Nona Farbehi +4

Spatial transcriptomics (ST) technologies enable gene expression profiling with spatial resolution, offering unprecedented insights into tissue organization and disease heterogenei…

cs.CL2025

STORYTELLER: An Enhanced Plot-Planning Framework for Coherent and Cohesive Story Generation

Jiaming Li, Yukun Chen, Ziqiang Liu +10

Stories are central to human culture, serving to share ideas, preserve traditions, and foster connections. Automatic story generation, a key advancement in artificial intelligence…

cs.CL2025

Expanding before Inferring: Enhancing Factuality in Large Language Models through Premature Layers Interpolation

Dingwei Chen, Ziqiang Liu, Feiteng Fang +6

Large Language Models (LLMs) demonstrate remarkable capabilities in text understanding and generation. However, their tendency to produce factually inconsistent outputs, commonly r…

q-bio.GN2025

Interpretable graph-based models on multimodal biomedical data integration: A technical review and benchmarking

Alireza Sadeghi, Farshid Hajati, Ahmadreza Argha +3

Integrating heterogeneous biomedical data including imaging, omics, and clinical records supports accurate diagnosis and personalised care. Graph-based models fuse such non-Euclide…

cs.CL2025

xJailbreak: Representation Space Guided Reinforcement Learning for Interpretable LLM Jailbreaking

Sunbowen Lee, Shiwen Ni, Chi Wei +7

Safety alignment mechanism are essential for preventing large language models (LLMs) from generating harmful information or unethical content. However, cleverly crafted prompts can…

cs.CL2024

PersonaMath: Boosting Mathematical Reasoning via Persona-Driven Data Augmentation

Jing Luo, Longze Chen, Run Luo +12

While closed-source Large Language Models (LLMs) demonstrate strong mathematical problem-solving abilities, open-source models still face challenges with such tasks. To bridge this…

cs.LG2024

ETAGE: Enhanced Test Time Adaptation with Integrated Entropy and Gradient Norms for Robust Model Performance

Afshar Shamsi, Rejisa Becirovic, Ahmadreza Argha +3

Test time adaptation (TTA) equips deep learning models to handle unseen test data that deviates from the training distribution, even when source data is inaccessible. While traditi…

cs.CL2024

Lower Layers Matter: Alleviating Hallucination via Multi-Layer Fusion Contrastive Decoding with Truthfulness Refocused

Dingwei Chen, Feiteng Fang, Shiwen Ni +6

Large Language Models (LLMs) have demonstrated exceptional performance across various natural language processing tasks. However, they occasionally generate inaccurate and counterf…

q-bio.GN2022★ 9 cited

Deep Learning in Spatially Resolved Transcriptomics: A Comprehensive Technical View

Roxana Zahedi Nasab, Mohammad Reza Eftekhariyan Ghamsari, Ahmadreza Argha +6

Spatially resolved transcriptomics (SRT) has evolved rapidly through various technologies, enabling scientists to investigate both morphological contexts and gene expression profil…