4 papers
Rare Diseases, Common Dilemmas: LLMs Prioritize Equal Resource Distribution over Patient Benefit in Decision-Making
Minda Zhao, Xu Han, Rishabh Goel +6
Clinical decision-making often involves prioritizing ethical values, such as beneficence, non-maleficence, respecting a patient's autonomy, and justice. Recent work has begun to as…
What Does the AI Doctor Value? Auditing Pluralism in the Clinical Ethics of Language Models
Payal Chandak, Victoria Alkin, David Wu +11
Medicine is inherently pluralistic. Principles such as autonomy, beneficence, nonmaleficence, and justice routinely conflict, and such ethical dilemmas often sharply divide reasona…
Systematic Characterization of the Effectiveness of Alignment in Large Language Models for Categorical Decisions
Isaac Kohane
As large language models (LLMs) are deployed in high-stakes domains like healthcare, understanding how well their decision-making aligns with human preferences and values becomes c…
Implications of mappings between ICD clinical diagnosis codes and Human Phenotype Ontology terms
Amelia LM Tan, Rafael S Gonçalves, William Yuan +4
Objective: Integrating EHR data with other resources is essential in rare disease research due to low disease prevalence. Such integration is dependent on the alignment of ontologi…