activity
20202026
most citedThe stochastic digital human is now enrolling for in silico imaging trials -- Methods and tools for generating digital cohorts

13 citations · 35 across the 15 of their papers we have counts for

collaborators

17 papers

stat.ML2026

Latent Score-Based Bayesian Cramér-Rao Bound Estimation for High-Dimensional Imaging Systems

Evan Scope Crafts, Thomas Wynn, Seonyeong Park +2

We propose a data-driven framework for estimating the Bayesian Cramér-Rao bound (CRB) in high-dimensional imaging systems with complex, analytically intractable priors. Direct CRB…

cs.LG2026

A Learning-based Framework for Spatial Impulse Response Compensation in 3D Photoacoustic Computed Tomography

Kaiyi Yang, Seonyeong Park, Gangwon Jeong +4

Photoacoustic computed tomography (PACT) is a promising imaging modality that combines the advantages of optical contrast with ultrasound detection. Utilizing ultrasound transducer…

physics.med-ph2026

Benchmarking Deep Learning-Based Reconstruction Methods for Photoacoustic Computed Tomography with Clinically Relevant Synthetic Datasets

Panpan Chen, Seonyeong Park, Gangwon Jeong +3

Deep learning (DL)-based image reconstruction methods for photoacoustic computed tomography (PACT) have developed rapidly in recent years. However, most existing methods have not e…

physics.med-ph2025

Stochastic numerical head phantoms to enable virtual imaging studies of transcranial photoacoustic computed tomography

Hsuan-Kai Huang, Joseph Kuo, Seonyeong Park +3

Transcranial photoacoustic computed tomography (PACT) is an emerging neuroimaging modality, but skull-induced aberrations can result in severe image artifacts if not compensated fo…

physics.med-ph2025

Application of a Virtual Imaging Framework for Investigating a Deep Learning-Based Reconstruction Method for 3D Quantitative Photoacoustic Computed Tomography

Refik Mert Cam, Seonyeong Park, Umberto Villa +1

Quantitative photoacoustic computed tomography (qPACT) is a promising imaging modality for estimating physiological parameters such as blood oxygen saturation. However, developing…

physics.optics2025★ 3 cited

LensPlus: A High Space-bandwidth Optical Imaging Technique

Neha Goswami, Mark A. Anastasio

The space-bandwidth product (SBP) imposes a fundamental limitation in achieving high-resolution and large field-of-view image acquisitions simultaneously. High-NA objectives provid…

eess.IV2025

Learned Correction Methods for Ultrasound Computed Tomography Imaging Using Simplified Physics Models

Luke Lozenski, Hanchen Wang, Fu Li +4

Ultrasound computed tomography (USCT) is an emerging modality for breast imaging. Image reconstruction methods that incorporate accurate wave physics produce high resolution quanti…

physics.med-ph2025

Estimating Task-based Performance Bounds for Accelerated MRI Image Reconstruction Methods by Use of Learned-Ideal Observers

Kaiyan Li, Prabhat Kc, Hua Li +3

Medical imaging systems are commonly assessed and optimized by the use of objective measures of image quality (IQ). The performance of the ideal observer (IO) acting on imaging mea…

physics.med-ph2024

Learning a Filtered Backprojection Reconstruction Method for Photoacoustic Computed Tomography with Hemispherical Measurement Geometries

Panpan Chen, Seonyeong Park, Refik Mert Cam +4

In certain three-dimensional (3D) applications of photoacoustic computed tomography (PACT), including \textit{in vivo} breast imaging, hemispherical measurement apertures that encl…

physics.med-ph2024

Optimizing Quantitative Photoacoustic Imaging Systems: The Bayesian Cramér-Rao Bound Approach

Evan Scope Crafts, Mark A. Anastasio, Umberto Villa

Quantitative photoacoustic computed tomography (qPACT) is an emerging medical imaging modality that carries the promise of high-contrast, fine-resolution imaging of clinically rele…

cs.LG2024★ 1 cited

Survey of Deep Learning and Physics-Based Approaches in Computational Wave Imaging

Youzuo Lin, Shihang Feng, James Theiler +7

Computational wave imaging (CWI) extracts hidden structure and physical properties of a volume of material by analyzing wave signals that traverse that volume. Applications include…

physics.ins-det2024★ 10 cited

Ortho-positronium Lifetime For Soft-tissue Classification

Ashish V. Avachat, Kholod H. Mahmoud, Anthony G. Leja +4

The objective of this work is to showcase the ortho-positronium lifetime as a probe for soft-tissue characterization. We employed positron annihilation lifetime spectroscopy to exp…

eess.IV2024

Identifying Functional Brain Networks of Spatiotemporal Wide-Field Calcium Imaging Data via a Long Short-Term Memory Autoencoder

Xiaohui Zhang, Eric C Landsness, Lindsey M Brier +6

Wide-field calcium imaging (WFCI) that records neural calcium dynamics allows for identification of functional brain networks (FBNs) in mice that express genetically encoded calciu…

eess.IV2024

Attention-Based CNN-BiLSTM for Sleep State Classification of Spatiotemporal Wide-Field Calcium Imaging Data

Xiaohui Zhang, Eric C. Landsness, Hanyang Miao +6

Background: Wide-field calcium imaging (WFCI) with genetically encoded calcium indicators allows for spatiotemporal recordings of neuronal activity in mice. When applied to the stu…

eess.IV2023

Deep learning-based image super-resolution of a novel end-expandable optical fiber probe for application in esophageal cancer diagnostics

Xiaohui Zhang, Mimi Tan, Mansour Nabil +5

Significance: Endoscopic screening for esophageal cancer may enable early cancer diagnosis and treatment. While optical microendoscopic technology has shown promise in improving sp…

cs.AI2023★ 13 cited

The stochastic digital human is now enrolling for in silico imaging trials -- Methods and tools for generating digital cohorts

A Badano, M Lago, E Sizikova +4

Randomized clinical trials, while often viewed as the highest evidentiary bar by which to judge the quality of a medical intervention, are far from perfect. In silico imaging trial…

physics.med-ph2020★ 8 cited

A signal detection model for quantifying over-regularization in non-linear image reconstruction

Emil Y. Sidky, John Paul Phillips, Weimin Zhou +5

Purpose: Many useful image quality metrics for evaluating linear image reconstruction techniques do not apply to or are difficult to interpret for non-linear image reconstruction.…