4 papers
Microscopic origin of macroscopic contractility in actin-myosin active gel models
Artur Alexandre, Nicola Dietler, Simone Cicolini +3
Actin filaments, crosslinkers and myosin molecular motors form contractile networks. For instance, the cell cortex is a thin network below the cell membrane ; contraction of the ce…
Mechanical properties of chiral actin filaments
Amir Khosravanizadeh, François Nédélec, Serge Dmitrieff
The mechanical properties of actin filaments are essential to their biological functions. Here, we introduce a highly coarse-grained model of actin filaments that preserves helicit…
Force-Velocity Relationship in Branched Actin Networks: Consequences of Entanglement, Drag and Stall Force
Magid Badaoui, Serge Dmitrieff
We investigate the growth of a branched actin network under load. Using a combination of simulations and theory, we show that the network adapts to the load and exhibits two regime…
Rotation-Beating dynamics of a driven flexible filament: role of motor protein properties
Amir Khosravanizadeh, Serge Dmitrieff
We have used numerical simulations to investigate how the properties of motor proteins control the dynamical behavior of a driven flexible filament. The filament is pinned at one e…