2 papers
cs.LG2026
THBKG: A Temporal Biomedical Knowledge Graph for Decision-Aligned Clinical Advancement Prediction
Pui Chung Siu, Claudia Cabrera, Mani Mudaliar +1
Inadequate target--disease linkage accounts for 40--50\% of Phase~II efficacy failures, so anticipating which programmes will advance would let sponsors back the hypotheses most li…
q-bio.QM2024
GATher: Graph Attention Based Predictions of Gene-Disease Links
David Narganes-Carlon, Anniek Myatt, Mani Mudaliar +1
Target selection is crucial in pharmaceutical drug discovery, directly influencing clinical trial success. Despite its importance, drug development remains resource-intensive, ofte…