3 papers
q-bio.QM2004
Predicting Genetic Regulatory Response Using Classification
Manuel Middendorf, Anshul Kundaje, Chris Wiggins +2
We present a novel classification-based method for learning to predict gene regulatory response. Our approach is motivated by the hypothesis that in simple organisms such as Saccha…
q-bio.QM2004
Predicting Genetic Regulatory Response using Classification: Yeast Stress Response
Manuel Middendorf, Anshul Kundaje, Chris Wiggins +2
We present a novel classification-based algorithm called GeneClass for learning to predict gene regulatory response. Our approach is motivated by the hypothesis that in simple orga…
q-bio.MN2004
Discriminative Topological Features Reveal Biological Network Mechanisms
Manuel Middendorf, Etay Ziv, Carter Adams +6
Recent genomic and bioinformatic advances have motivated the development of numerous random network models purporting to describe graphs of biological, technological, and sociologi…