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Separating mixtures of single-fiber orientation distributions for increased sensitivity to crossing white matter fibers
Adam M. Saunders, Gaurav Rudravaram, Michael E. Kim +10
Intro: Diffusion MRI allows for in vivo probing of brain tissue architecture via micron-level diffusion aggregated at the millimeter scale, but crossing white matter fibers decreas…
Large-Scale Deployment and Analytical Implications of Structured Quality Control in Diffusion Magnetic Resonance Imaging
Michael E. Kim, Chenyu Gao, Karthik Ramadass +17
Purpose: Diffusion MRI (dMRI) provides a diverse set of quantitative measures and derived datatypes to assess white matter microstructure and macrostructure. Coupled with the incre…
Evaluation of neuroCombat and deep learning harmonization for multi-site magnetic resonance neuroimaging in youth with prenatal alcohol exposure
Chloe Scholten, Elyssa M. McMaster, Adam M. Saunders +8
In cases of prevalent diseases and disorders, such as Prenatal Alcohol Exposure (PAE), multi-site data collection allows for increased study samples. However, multi-site studies in…
Harmonization mitigates diffusion MRI scanner effects in infancy: insights from the HEALthy Brain and Childhood Development (HBCD) study
Elyssa M. McMaster, Gaurav Rudravaram, Michael E. Kim +17
The HEALthy Brain and Childhood Development (HBCD) Study is an ongoing longitudinal initiative to understand population-level brain maturation; however, large-scale studies must ov…
Personalized White Matter Bundle Segmentation for Early Childhood
Elyssa M. McMaster, Michael E. Kim, Nancy R. Newlin +12
White matter segmentation methods from diffusion magnetic resonance imaging range from streamline clustering-based approaches to bundle mask delineation, but none have proposed a p…
Quality assurance of the Federal Interagency Traumatic Brain Injury Research (FITBIR) database for multi-site MRI analysis
Adam M. Saunders, Michael E. Kim, Gaurav Rudravaram +8
The Federal Interagency Traumatic Brain Injury Research (FITBIR) database is a centralized data repository for traumatic brain injury (TBI) research. It includes over 45,529 magnet…
Fully Differentiable dMRI Streamline Propagation in PyTorch
Jongyeon Yoon, Elyssa M. McMaster, Michael E. Kim +4
Diffusion MRI (dMRI) provides a distinctive means to probe the microstructural architecture of living tissue, facilitating applications such as brain connectivity analysis, modelin…
DeepFixel: Crossing white matter fiber identification through spherical convolutional neural networks
Adam M. Saunders, Lucas W. Remedios, Elyssa M. McMaster +6
Diffusion-weighted magnetic resonance imaging allows for reconstruction of models for structural connectivity in the brain, such as fiber orientation distribution functions (ODFs)…
Multipath cycleGAN for harmonization of paired and unpaired low-dose lung computed tomography reconstruction kernels
Aravind R. Krishnan, Thomas Z. Li, Lucas W. Remedios +12
Reconstruction kernels in computed tomography (CT) affect spatial resolution and noise characteristics, introducing systematic variability in quantitative imaging measurements such…