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q-bio.TO2025
A Multi-Scale Finite Element Method for Investigating Fiber Remodeling in Hypertrophic Cardiomyopathy
Mohammad Mehri, Kenneth S. Campbell, Lik Chuan Lee +1
A significant hallmark of hypertrophic cardiomyopathy (HCM) is fiber disarray, which is associated with various cardiac events such as heart failure. Quantifying fiber disarray rem…
q-bio.TO2024
Multi-Scale Fiber Remodeling in HCM Using a Stress-Based Fiber Reorientation Law
Mohammad Mehri, Hossein Sharifi, Kenneth S. Campbell +1
Quantifying fiber disarray, which is a prominent maladaptation associated with hypertrophic cardiomyopathy, remains critical to understanding the disease's complex pathophysiology.…