11 citations · 11 across the 5 of their papers we have counts for
5 papers
DNA handles bias force-dependent looping times
Wout Laeremans, Jef Hooyberghs, Wouter G. Ellenbroek
DNA loop formation is central to gene regulation, and its kinetics depend sensitively on mechanical tension. In both single-molecule experiments and biological settings, this tensi…
Synthetic design of force-responsive hydrogels with ring-forming catch bonds
Wout Laeremans, Wouter G. Ellenbroek
Catch bonds are interactions whose lifetimes increase under mechanical load, a counterintuitive behaviour that underlies diverse biological processes. Translating this mechanism to…
Theoretical Models for Tension-Dependent DNA Looping Time
Wout Laeremans, Wouter G Ellenbroek
The influence of tension on DNA looping has been studied both experimentally and theoretically in the past. However, different theoretical models have yielded different predictions…
Polymer dynamics under tension: mean first passage time for looping
Wout Laeremans, Anne Floor den Ouden, Jef Hooyberghs +1
This study deals with polymer looping, an important process in many chemical and biological systems. We investigate basic questions on the looping dynamics of a polymer under tensi…
Insights into elastic properties of coarse-grained DNA models: q-stiffness of cgDNA vs. cgDNA+
Wout Laeremans, Midas Segers, Aderik Voorspoels +2
Coarse-grained models have emerged as valuable tools to simulate long DNA molecules while maintaining computational efficiency. These models aim at preserving interactions among co…