4 papers · 1 filter
Causal machine learning reveals age-dependent radiation dose effects on mandibular osteoradionecrosis
Jingyuan Chen, Yunze Yang, Olivia M. Muller +8
Distinguishing causal relationships from statistical correlations remains a fundamental challenge in clinical research, limiting the translation of observational findings into inte…
Dose-LET Interactions Predict Capsular Contracture After Proton Postmastectomy Radiation Therapy
Jingyuan Chen, Zeliang Ma, Meiyun Cao +9
Pencil beam scanning (PBS) proton therapy provides highly conformal dose distributions that are increasingly leveraged for postmastectomy radiation therapy (PMRT) to reduce cardiop…
Critical review of patient outcome study in head and neck cancer radiotherapy
Jingyuan Chen, Yunze Yang, Chenbin Liu +8
Rapid technological advances in radiation therapy have significantly improved dose delivery and tumor control for head and neck cancers. However, treatment-related toxicities cause…
Enabling Clinical Use of Linear Energy Transfer in Proton Therapy for Head and Neck Cancer -- A Review of Implications for Treatment Planning and Adverse Events Study
Jingyuan Chen, Yunze Yang, Hongying Feng +12
Proton therapy offers significant advantages due to its unique physical and biological properties, particularly the Bragg peak, enabling precise dose delivery to tumors while spari…