4 papers
CEHR-GPT: Generating Electronic Health Records with Chronological Patient Timelines
Chao Pang, Xinzhuo Jiang, Nishanth Parameshwar Pavinkurve +8
Synthetic Electronic Health Records (EHR) have emerged as a pivotal tool in advancing healthcare applications and machine learning models, particularly for researchers without dire…
Bayesian Posterior Interval Calibration to Improve the Interpretability of Observational Studies
Jami J. Mulgrave, David Madigan, George Hripcsak
Observational healthcare data offer the potential to estimate causal effects of medical products on a large scale. However, the confidence intervals and p-values produced by observ…
Evaluating the impact of instrumental variables in propensity score models using synthetic and negative control experiments
Yuxi Tian, Nicole Pratt, Laura L Hester +3
In pharmacoepidemiology research, instrumental variables (IVs) are variables that strongly predict treatment but have no causal effect on the outcome of interest except through the…
An Open-Source Knowledge Graph Ecosystem for the Life Sciences
Tiffany J. Callahan, Ignacio J. Tripodi, Adrianne L. Stefanski +29
Translational research requires data at multiple scales of biological organization. Advancements in sequencing and multi-omics technologies have increased the availability of these…