247 citations · 556 across the 7 of their papers we have counts for
3 papers · 1 filter
Exact solution of a model DNA-inversion genetic switch with orientational control
Paolo Visco, Rosalind J. Allen, Martin R. Evans
DNA inversion is an important mechanism by which bacteria and bacteriophage switch reversibly between phenotypic states. In such switches, the orientation of a short DNA element is…
Reaction coordinates for the flipping of genetic switches
M. J. Morelli, S. Tanase-Nicola, R. J. Allen +1
We present a detailed analysis, based on the Forward Flux Sampling (FFS) simulation method, of the switching dynamics and stability of two models of genetic toggle switches, consis…
Sampling rare switching events in biochemical networks
Rosalind J. Allen, Patrick B. Warren, Pieter Rein ten Wolde
Bistable biochemical switches are ubiquitous in gene regulatory networks and signal transduction pathways. Their switching dynamics, however, are difficult to study directly in exp…